Irrespective of the fact that Sildenafil and Avanafil medications are related to the same class of drugs which is used for the treatment of erectile dysfunction in male patients, there are some key differences among them which we are going to discuss in this blog. Basic functionality of these tablets can be understood as the drugs from class of PDE5 inhibitors whose main function is to increase the flow of blood to the penis and region around it to facilitate better and longer erection in males. There are some key facts which separate these two medicines that we have researched for you to put it in this blog so that you can choose the right option as per the requirements.


It is a well-known fact that effectiveness of any tablet is very difficult to measure as it varies from person to person depending on a large number of facts like body composition, food habits, pre-medication and state of mind of the user. However, on the basis of several clinical trials and research programs, it has been found that in most patients, Avanafil acts faster as compared to Sildenafil.


Where the tablet of Sildenafil may take up to 60 minutes to show the effect on a patient, Avanafil may start acting in the body within 15 minutes. Once consumed, Sildenafil may last for 6 hours which is a smaller duration if compared to that of Avanafil which lasts up to 8 hours after consumption.


A tablet of Avanafil can be taken with or without meals because food does not affect its rate of absorption in the body of the user. On the contrary, Sildenafil if taken after a full fat meal may start to act after a longer duration than expected, as food slows the absorption rate of this medicine in the human body.


As we have already mentioned above, both of these tablets are used for the same treatment and also belong to same class of drugs, their side effects are also common in nature. Nasal congestion, mild headache, difficulty in digestion of food, flushes and dizziness are some common side effects of these two medicines. 


The dosage of Sildenafil starts generally from 50 mg per day and can be increased to 100 mg per day under the supervision of medical practitioner. On the other hand, a tablet of Avanafil is taken in the 100 mg dose form commonly, which can be increased up to 200 mg per day as per the needs and health condition of the user.


Whereas Sildenafil has got popular by the name of Viagra worldwide, Avanafil has gained popularity on the basis of its action mechanism which people love the most about. Avanafil is the need of every individual today who is suffering from erectile dysfunction because it acts faster if compared to other tablets in its class and at the same time it lasts longer than other medications as well.



Tadalafil and Sildenafil are used for the treatment of a medical condition called erectile dysfunction which is commonly called ED. However, these medicines are related to separate class of drugs on the basis of their specification and composition. We will see a detailed comparison of these medicines in this blog.


Tadalafil and Sildenafil are both linked to the class of PDE5 inhibitors, but there is a basic difference between their chemical compositions and also Tadalafil acts for a longer time as compared to Sildenafil.


Tadalafil – This medicine is known by the name of Cialis.

Sildenafil – The brand name of Sildenafil is popularly called Viagra.


Whereas a Sildenafil tablet reacts with the human body within thirty to sixty minutes of consuming, Tadalafil takes effect one to two hours after consumption and hence it lasts longer too.


Sildenafil – This medicine is taken about 30 to 60 minutes prior to getting involved in sexual activity.

Tadalafil – This tablet gives the choice to the user of taking it on a daily basis in the form of a lower dose or only consuming it an hour or two before getting involved in sexual activity.

Food Habits

Sildenafil – Users of this medicine must not take any meal containing high-fat as it may increase the time required for the medication to take effect. 

Tadalafil – Unlike the Sildenafil tablet, food habits rarely affect the results and course of action of this medication.

Side Effects

The most common side effects for both of these medicines are digestive problems, nasal congestion, dizziness, headache and flushing. It should be noted that the severity of these side effects may vary from patient to patient on the basis of dosage and their body composition.

Dosage Available

Sildenafil is generally available in 25mg, 50mg and 100mg dosage tablets.

Tadalafil is easily available in 2.5mg, 5mg, 10mg and 20mg tablet form respectively.

Points to Remember

A patient must ensure that none of these medications is taken with other medicines like nitroglycerine because it may result in lowering the blood pressure severely and may prove to be fatal in rare cases depending on body composition of the user taking this pill.

It is always a good idea to consult with a physician about any previous medical condition or allergies before taking this tabletin order to ensure that there are no harmful effects of taking either of these medicines on the health of the user.


This blog is only designed to present an overview of these medicines in the present scenario. However, it is strongly advised that the patient takes these medications under direct supervision of a doctor or a certified medical practitioner to avoid any side effects from surfacing.

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