Tadalafil and Sildenafil are used for the treatment of a medical condition called erectile dysfunction which is commonly called ED. However, these medicines are related to separate class of drugs on the basis of their specification and composition. We will see a detailed comparison of these medicines in this blog.


Tadalafil and Sildenafil are both linked to the class of PDE5 inhibitors, but there is a basic difference between their chemical compositions and also Tadalafil acts for a longer time as compared to Sildenafil.


Tadalafil – This medicine is known by the name of Cialis.

Sildenafil – The brand name of Sildenafil is popularly called Viagra.


Whereas a Sildenafil tablet reacts with the human body within thirty to sixty minutes of consuming, Tadalafil takes effect one to two hours after consumption and hence it lasts longer too.


Sildenafil – This medicine is taken about 30 to 60 minutes prior to getting involved in sexual activity.

Tadalafil – This tablet gives the choice to the user of taking it on a daily basis in the form of a lower dose or only consuming it an hour or two before getting involved in sexual activity.

Food Habits

Sildenafil – Users of this medicine must not take any meal containing high-fat as it may increase the time required for the medication to take effect. 

Tadalafil – Unlike the Sildenafil tablet, food habits rarely affect the results and course of action of this medication.

Side Effects

The most common side effects for both of these medicines are digestive problems, nasal congestion, dizziness, headache and flushing. It should be noted that the severity of these side effects may vary from patient to patient on the basis of dosage and their body composition.

Dosage Available

Sildenafil is generally available in 25mg, 50mg and 100mg dosage tablets.

Tadalafil is easily available in 2.5mg, 5mg, 10mg and 20mg tablet form respectively.

Points to Remember

A patient must ensure that none of these medications is taken with other medicines like nitroglycerine because it may result in lowering the blood pressure severely and may prove to be fatal in rare cases depending on body composition of the user taking this pill.

It is always a good idea to consult with a physician about any previous medical condition or allergies before taking this tabletin order to ensure that there are no harmful effects of taking either of these medicines on the health of the user.


This blog is only designed to present an overview of these medicines in the present scenario. However, it is strongly advised that the patient takes these medications under direct supervision of a doctor or a certified medical practitioner to avoid any side effects from surfacing.

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